diff --git a/biology/ugene/Makefile b/biology/ugene/Makefile
index 52036dcf0c70..d0a877754715 100644
--- a/biology/ugene/Makefile
+++ b/biology/ugene/Makefile
@@ -1,7 +1,7 @@
 # Created by: Hannes Hauswedell <h2+fbsdports@fsfe.org>
 
 PORTNAME=	ugene
-PORTVERSION=	40.0
+PORTVERSION=	40.1
 CATEGORIES=	biology science
 
 MAINTAINER=	h2+fbsdports@fsfe.org
diff --git a/biology/ugene/distinfo b/biology/ugene/distinfo
index 645944ea4647..5eff6f289b9d 100644
--- a/biology/ugene/distinfo
+++ b/biology/ugene/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1631110733
-SHA256 (ugeneunipro-ugene-40.0_GH0.tar.gz) = 7a2f06141d571f45ce61e68af0a2456a3b3892b2d97104ec7ddfd1113b447c0f
-SIZE (ugeneunipro-ugene-40.0_GH0.tar.gz) = 28789225
+TIMESTAMP = 1633934483
+SHA256 (ugeneunipro-ugene-40.1_GH0.tar.gz) = 92b954449f697957c6b6b2da803ba6ae9ad546f44c584bbb2ab8600ac8b45a6e
+SIZE (ugeneunipro-ugene-40.1_GH0.tar.gz) = 28791083