diff --git a/MOVED b/MOVED
index d2f95c93646e..614170eb0b49 100644
--- a/MOVED
+++ b/MOVED
@@ -4223,3 +4223,4 @@ www/py-flask-security||2025-03-31|Has expired: Depends on expired devel/py-pytes
 devel/py-aiocontextvars||2025-03-31|Has expired: Depends on expired devel/py-pytest-runner
 finance/odoo||2025-03-31|Has expired: Depends on expired print/py-pypdf2
 converters/libutf-8||2025-03-31|Has expired: Upstream disapeared and distfile is no more available
+science/py-moltemplate||2025-03-31|Has expired: Depends on expired devel/py-pytest-runner
diff --git a/science/Makefile b/science/Makefile
index c35f2114c848..d019239960f4 100644
--- a/science/Makefile
+++ b/science/Makefile
@@ -374,7 +374,6 @@
     SUBDIR += py-mmcif
     SUBDIR += py-mmtf-python
     SUBDIR += py-molmod
-    SUBDIR += py-moltemplate
     SUBDIR += py-mp-api
     SUBDIR += py-mpcontribs-client
     SUBDIR += py-mplhep
diff --git a/science/py-moltemplate/Makefile b/science/py-moltemplate/Makefile
deleted file mode 100644
index e0d41c2bbe4e..000000000000
--- a/science/py-moltemplate/Makefile
+++ /dev/null
@@ -1,47 +0,0 @@
-PORTNAME=	moltemplate
-DISTVERSIONPREFIX=	v
-DISTVERSION=	2.22.0
-PORTREVISION=	1
-CATEGORIES=	science python
-PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
-
-MAINTAINER=	yuri@FreeBSD.org
-COMMENT=	Tool to prepare simulations of molecules, complex molecular assemblies
-WWW=		https://www.moltemplate.org/ \
-		https://github.com/jewettaij/moltemplate
-
-LICENSE=	MIT
-LICENSE_FILE=	${WRKSRC}/LICENSE.md
-
-DEPRECATED=	Depends on expired devel/py-pytest-runner
-EXPIRATION_DATE=2025-03-31
-
-BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pytest-runner>0:devel/py-pytest-runner@${PY_FLAVOR}
-RUN_DEPENDS=	${PYNUMPY} \
-		bash:shells/bash
-TEST_DEPENDS=	shunit2>0:devel/shunit2
-
-USES=		python shebangfix
-USE_PYTHON=	distutils concurrent autoplist
-
-USE_GITHUB=	yes
-GH_ACCOUNT=	jewettaij
-
-SHEBANG_FILES=	moltemplate/scripts/molc.sh #shunit2/shunit2
-
-NO_ARCH=	yes
-
-BINARY_ALIAS=	python3=${PYTHON_CMD}
-
-TEST_ENV=	${MAKE_ENV} PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR} PATH=${STAGEDIR}${LOCALBASE}/bin:${PATH}
-
-do-test: # testsuite instructions: https://github.com/jewettaij/moltemplate/issues/65#issuecomment-1022740972
-	@cd ${WRKSRC} && \
-		([ -e shunit2 ] || (${MKDIR} tests/shunit2 && ${RM} tests/shunit2/shunit2 && ${LN} -s ${LOCALBASE}/bin/shunit2 tests/shunit2/shunit2)) && \
-		${SETENV} ${TEST_ENV} bash tests/test_read_coords_pdb.sh && \
-		${SETENV} ${TEST_ENV} bash tests/test_ltemplify.sh && \
-		${SETENV} ${TEST_ENV} bash tests/test_oplsaa.sh && \
-		${SETENV} ${TEST_ENV} bash tests/test_compass.sh && \
-		${SETENV} ${TEST_ENV} python3 tests/test_genpoly_lt.py
-
-.include <bsd.port.mk>
diff --git a/science/py-moltemplate/distinfo b/science/py-moltemplate/distinfo
deleted file mode 100644
index d78bf36bcf8f..000000000000
--- a/science/py-moltemplate/distinfo
+++ /dev/null
@@ -1,3 +0,0 @@
-TIMESTAMP = 1733724285
-SHA256 (jewettaij-moltemplate-v2.22.0_GH0.tar.gz) = d262abb8d105118417ebb607ac8a1d2bafcb867985f606dc4c0a499789a35a09
-SIZE (jewettaij-moltemplate-v2.22.0_GH0.tar.gz) = 9626611
diff --git a/science/py-moltemplate/pkg-descr b/science/py-moltemplate/pkg-descr
deleted file mode 100644
index f56ed6c748cd..000000000000
--- a/science/py-moltemplate/pkg-descr
+++ /dev/null
@@ -1,16 +0,0 @@
-Moltemplate is a general cross-platform text-based molecule builder for LAMMPS,
-an extremely flexible and customizable molecular dynamics engine.
-
-Moltemplate was designed for inventing new kinds of complex coarse-grained toy
-models of molecules, molecular machines, and assemblies. However it is well
-suited for preparing realistic all-atom simulations as well. It supports a wide
-variety of existing force fields and models including: OPLS, AMBER(GAFF,GAFF2),
-COMPASS, LOPLS(2015), EFF, TraPPE(1998), MOLC, mW, ELBA(water), and oxDNA2.
-However it can be used to build molecules using any of the force fields (and
-atom styles) available in LAMMPS, including new force fields created by
-modifying the LAMMPS source code. Molecules can be copied, combined, and linked
-together as building-blocks to define new molecules (hierarchically). Once
-built, individual molecules and subunits can be customized (atoms, bonds, and
-subunits can be moved and deleted). Moltemplate is currently interoperable with:
-VMD , PACKMOL , OVITO , CellPACK , VIPSTER , and the ATB molecule server
-(by using the ltemplify.py converter).