diff --git a/science/pyteomics/Makefile b/science/pyteomics/Makefile
index 03cc2efb18dd..5b478ceef8d7 100644
--- a/science/pyteomics/Makefile
+++ b/science/pyteomics/Makefile
@@ -1,7 +1,7 @@
 # $FreeBSD$
 
 PORTNAME=	pyteomics
-PORTVERSION=	2.2.0
+PORTVERSION=	2.2.1
 CATEGORIES=	science python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
diff --git a/science/pyteomics/distinfo b/science/pyteomics/distinfo
index 9b36be2fbe00..bb267d585a35 100644
--- a/science/pyteomics/distinfo
+++ b/science/pyteomics/distinfo
@@ -1,2 +1,2 @@
-SHA256 (pyteomics-2.2.0.tar.gz) = 1b4c08495bcd6aa9891db9e0fe9f979058cf1052a5f6d7d6e94e87980c2100b1
-SIZE (pyteomics-2.2.0.tar.gz) = 73354
+SHA256 (pyteomics-2.2.1.tar.gz) = 0172872ff4c6a28878de4692d1472669b4ab94a21261dafa6d9fba0725a95b4d
+SIZE (pyteomics-2.2.1.tar.gz) = 74020