diff --git a/biology/prodigy-lig/Makefile b/biology/prodigy-lig/Makefile
index 89210a5e07ba..ec7ceaea67be 100644
--- a/biology/prodigy-lig/Makefile
+++ b/biology/prodigy-lig/Makefile
@@ -1,6 +1,6 @@
 PORTNAME=	prodigy-lig
 DISTVERSIONPREFIX=	v
-DISTVERSION=	1.1.2
+DISTVERSION=	1.1.3
 CATEGORIES=	biology python
 
 MAINTAINER=	yuri@FreeBSD.org
@@ -13,6 +13,7 @@ LICENSE_FILE=	${WRKSRC}/LICENSE
 BUILD_DEPENDS=	${PYNUMPY} \
 		${PYTHON_PKGNAMEPREFIX}biopython>0:biology/py-biopython@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}poetry-core>0:devel/py-poetry-core@${PY_FLAVOR}
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}biopython>0:biology/py-biopython@${PY_FLAVOR}
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}coverage>0:devel/py-coverage@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}hypothesis>0:devel/py-hypothesis@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-cov>0:devel/py-pytest-cov@${PY_FLAVOR}
diff --git a/biology/prodigy-lig/distinfo b/biology/prodigy-lig/distinfo
index 67a9756754b9..312bf1d82460 100644
--- a/biology/prodigy-lig/distinfo
+++ b/biology/prodigy-lig/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1728016554
-SHA256 (haddocking-prodigy-lig-v1.1.2_GH0.tar.gz) = 6b37535f105c01402cd922d046e31e4ae0dc21fa45ef6b5e352835bbcf3df036
-SIZE (haddocking-prodigy-lig-v1.1.2_GH0.tar.gz) = 157025
+TIMESTAMP = 1729012650
+SHA256 (haddocking-prodigy-lig-v1.1.3_GH0.tar.gz) = 2dc553beea82259feb5d1cce104f830e48c8b7d64a653818a3e49a84fbc68c64
+SIZE (haddocking-prodigy-lig-v1.1.3_GH0.tar.gz) = 157035