diff --git a/biology/htslib/Makefile b/biology/htslib/Makefile
index d326ae2b0b65..ec7ab0ab4d8d 100644
--- a/biology/htslib/Makefile
+++ b/biology/htslib/Makefile
@@ -16,7 +16,7 @@ LICENSE_FILE=	${WRKSRC}/LICENSE
 LIB_DEPENDS=	libdeflate.so:archivers/libdeflate
 TEST_DEPENDS=	bash:shells/bash
 
-USES=		autoreconf gmake localbase pathfix perl5 shebangfix tar:bzip2
+USES=		autoreconf cpe gmake localbase pathfix perl5 shebangfix tar:bzip2
 USE_PERL5=	test
 USE_LDCONFIG=	yes